| Day | Week | Home | Result | Away |
|---|---|---|---|---|
| 2024-08-31 | 1 | Inter Milano | 5 - 0 | Sampdoria |
| 2024-09-15 | 2 | Sampdoria | 1 - 1 | Lazio |
| 2024-09-22 | 3 | Fiorentina | 4 - 0 | Sampdoria |
| 2024-09-28 | 4 | Como | 1 - 1 | Sampdoria |
| 2024-10-05 | 5 | Sampdoria | 0 - 2 | Juventus |
| 2024-10-13 | 6 | AC Milan | 1 - 0 | Sampdoria |
| 2024-10-19 | 7 | Sampdoria | 0 - 0 | Napoli |
| 2024-11-03 | 8 | Sampdoria | 1 - 5 | Roma |
| 2024-11-09 | 9 | Sassuolo | 3 - 0 | Sampdoria |
| 2024-11-16 | 10 | Sampdoria | 0 - 3 | Inter Milano |
| 2024-11-23 | 11 | Lazio | 0 - 0 | Sampdoria |
| 2024-12-07 | 12 | Sampdoria | 1 - 3 | Fiorentina |
| 2024-12-15 | 13 | Sampdoria | 1 - 2 | Como |
| 2025-01-11 | 14 | Juventus | 3 - 0 | Sampdoria |
| 2025-01-19 | 15 | Sampdoria | 2 - 2 | AC Milan |
| 2025-01-26 | 16 | Napoli | 0 - 1 | Sampdoria |
| 2025-02-01 | 17 | Roma | 4 - 0 | Sampdoria |
| 2025-02-09 | 18 | Sampdoria | 0 - 2 | Sassuolo |
| 2025-03-01 | RR1 | Lazio | 3 - 0 | Sampdoria |
| 2025-03-15 | RR3 | Sampdoria | 1 - 1 | Napoli |
| 2025-03-23 | RR4 | Como | 2 - 2 | Sampdoria |
| 2025-03-30 | RR5 | Sampdoria | 2 - 5 | Sassuolo |
Sampdoria
2024-25シーズン